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Advances in Clinical Trial Biostatistics - Nancy L. Geller

Contents


Part I METHODS FOR EARLY TRIALS
1. Bayesian Methods for Cancer Phase I Clinical Trials
James S. Babb and Andre´ Rogatko
2. Design of Early Trials in Stem Cell Transplantation:
A Hybrid Frequentist-Bayesian Approach
Nancy L. Geller, Dean Follmann, Eric S. Leifer, and
Shelly L. Carter

Part II METHODS FOR RANDOMIZED TRIALS
3. Design and Analysis of Therapeutic Equivalence Trials
Richard M. Simon
4. Adaptive Two-Stage Clinical Trials
Michael A. Proschan
5. Design and Analysis of Cluster Randomization Trials
David M. Zucker

6. Design and Analysis of Clinical Trials with Multiple
Endpoints
Nancy L. Geller
7. Subgroups and Interactions
Dean Follmann
8. A Class of Permutation Tests for Some Two-Sample
Survival Data Problems
Joanna H. Shih and Michael P. Fay
9. Bayesian Reporting of Clinical Trials
Simon Weeden, Laurence S. Freedman, and Mahesh
Parmar
Part III MORE COMPLEX PROBLEMS
10. Methods Incorporating Compliance in Treatment
Evaluation
Juni Palmgren and Els Goetghebeur
11. Analysis of Longitudinal Data with Missingness
Paul S. Albert and Margaret C. Wu
12. Statistical Issues Emerging from Clinical Trials in HIV
Infection
Abdel G. Babiker and Ann Sarah Walker

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